Tepmetko
Tepotinib Hcl
What is Tepmetko used for?
This medication is used to treat a certain type of lung cancer (non-small cell lung cancer). Tepotinib belongs to a class of drugs known as kinase inhibitors. It works by slowing or stopping the growth of cancer cells.
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Tepmetko Frequently Asked Questions
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call 1-800-222-1222. Canada residents can call 1-844-764-7669.
Do not share this medication with others.
Lab and/or medical tests (such as liver function, complete blood count, amylase/lipase level) should be done while you are taking this medication. Keep all medical and lab appointments. Consult your doctor for more details.
Store in the original package at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
Read the Patient Information Leaflet if available from your pharmacist before you start taking tepotinib and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth with food as directed by your doctor, usually once daily. Swallow the tablets whole. Do not chew, crush, or split the tablets.
If you have trouble swallowing the tablets whole, place the tablets in a cup with 30 milliliters (1 ounce) of non-carbonated water. Stir well until the tablets break into small pieces. Do not crush the tablets. The tablets will not completely dissolve. Drink all of the mixture without chewing, right away or within 1 hour. Add more water (30 milliliters/1 ounce) to the cup and drink all of the mixture to make sure you are getting all of the drug. Use only non-carbonated water for mixing. Do not prepare a supply ahead of time.
If you are giving this mixture through a tube into the stomach (such as a nasogastric tube), ask your health care professional for detailed instructions on how to give it.
If you vomit after taking a dose, do not take another dose. Take your next dose at your regular scheduled time.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.
The dosage is based on your medical condition and response to treatment. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.
Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets.
Nausea, vomiting, diarrhea or constipation, swelling, tiredness, abdominal pain, muscle/joint pain, and loss of appetite may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
People using this medication may have serious side effects. However, you have been prescribed this drug because your doctor has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk.
This medication may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as sore throat that doesn't go away, fever, chills, cough).
Tepotinib can cause severe (possibly fatal) lung problems (interstitial lung disease/pneumonitis). Tell your doctor right away if you have any symptoms of lung problems (such as cough, shortness of breath, trouble breathing, fever).
Tepotinib may cause serious (possibly fatal) liver disease. Your doctor will test your liver function while you are taking this medication. Tell your doctor right away if you have any symptoms of liver damage, such as nausea/vomiting that doesn't stop, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at MedWatch: The FDA Safety Information and Adverse Event Reporting Program.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Before taking tepotinib, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver problems, lung or breathing problems other than your lung cancer, recent/current infection.
Tepotinib can make you more likely to get infections or may make current infections worse. Stay away from anyone who has an infection that may easily spread (such as chickenpox, COVID-19, measles, flu). Talk to your doctor if you have been exposed to an infection or for more details.
Tell your health care professional that you are using tepotinib before having any immunizations/vaccinations. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets.
Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while taking tepotinib. Tepotinib may harm an unborn baby. Your doctor should order a pregnancy test before you start this medication. Men and women using this medication should ask about reliable forms of birth control during treatment and for 1 week after the last dose. If you or your partner becomes pregnant, talk to your doctor right away about the risks and benefits of this medication.
It is unknown if this drug passes into breast milk. Because of the possible risk to the infant, breastfeeding is not recommended while using this drug and for 1 week after the last dose. Consult your doctor before breastfeeding.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
If you miss a dose, take it as soon as you remember. If it is within 8 hours of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Your condition can cause complications in a medical emergency. For information about enrolling in MedicAlert, call 1-888-633-4298 (US) or 1-800-668-1507 (Canada).